高理钱

  • 2017年任药学院(深圳)百人计划副教授、硕导 。2012年8月新加坡国立大学化学系博士毕业,师从国际知名的化学生物学领域的专家姚少钦教授和Dr. Mahesh Uttamchandani。自2012起担任6个国际期刊的编委(Editorial board member),2个国际期刊专刊的客座主编(Lead guest editor)和客座编辑(Co-guest editor)和多个重要国际期刊的审稿人。
  • 学科专业:药物化学
  • 研究方向:高通量药物筛选和创新药物研发,多肽药物,化学生物学,生物/纳米材料在转化医学中的应用
  • 邮箱:gaolq@mail.sysu.edu.cn
  • 代表性论文:(# equal contribution, *corresponding author)

1. Wang J #, Gao L #, Lee YM#, Kalesh KA, Ong YS, Lim J, Jee JE, Sun H, Lee SS, Hua ZC, Lin QS, “Target identification of natural and traditional medicine with quantitative chemical proteomics approaches”, Pharmacology & Therapeutics (2016), 162:10-22.

2. Gao L, Uttamchandani M, Yao SQ, “Comparative Proteomic Profiling of Mammalian Cell Lysates Using Phosphopeptide Microarrays”, Chem Commun (2012), 48:2240-2242.

3. Ling D#, Gao L #, J. Wang #, Shokouhimehr M, Liu J, Yu Y, Hackett MJ, So PK, Zheng B, Yao Z, Xia J, Hyeon T, “A General Strategy for Site-directed Enzyme Immobilization using NiO Nanoparticle Decorated Mesoporous Silica”, Chemistry-A European Journal (2014), 20:7916–7921.

4. Gao L, Chen J, Hu Y, Sun H, Ong YS, Zhang J, Chai Z, Lee SS, “Characterization and Preclinical Perspectives of Organic Small Molecule Drug Metabolites in Drug-Drug Interactions”, Current Organic Chemistry (2016), 20 (17):1827-1834.

5. Gao L, Yu Z, Meng D, Zheng F, Ong YS, Miao P, Lee SS, Wen LP, “Analogue of Melanotan II (MTII): A Novel Melanotropin with Superpotent Action on Frog Skin”, Protein & Peptide Letters (2015), 22:762-766.

6.Gao L, Sun H, Yao SQ, “Activity-Based High-Throughput Determination of PTPs Substrate Specificity Using a Phosphopeptide Microarray”, Biopolymers (2010), 94: 810–819.

7. Liu F, Wang JH, Liu L, Ding S, Fu M, Deng L, Gao L*, “Developing a fluorescence coupled capillary electrophoresis based method to probe interactions between QDs and colorectal cancer targeting peptides”, Electrophoresis (2016), 37(15-16):2170-2174.

8. Wang JH, Zhang C, Liu L, Qiu L, Ding S, Fu M, Gao L*, Jiang P, "A capillary electrophoresis method to explore the self-assembly of a novel polypeptide ligand with quantum dots”, Electrophoresis (2016), 37(15-16):2156-2162.

9. Wang J, Li J, Li JC, Liu F, Gu Y, Fan J, Dong B, Wang C, Qiu L, Gao L*, Lee SS, Jiang P, “Organic Chemistry Tool for Nanoparticles Monofunctinalization and Their Biomedical Applications”, Current Organic Chemistry (2016), 20 (17): 1786-1796.

10. Yu Z, Xu Q, Dong CB, Lee SS, Gao L*, Li Y, D’Ortenzio M, Wu J, “Self-assembling peptide nanofibrous hydrogel as a versatile drug delivery platform”, Current Pharmaceutical Design (2015), 21(29):4342-4354.