蒋芬

  • 2017年任药学院(深圳)特聘副研究员 。韩国仁济大学医学院药理学博士,首尔大学医学院药理学博士后。2013年在韩国食品药品安全处担任高级研究员。2014年担任韩美药物临床开发顾问。现任韩国仁济大学医学院客座教授。
  • 学科专业:临床药理学、遗传药理学
  • 研究方向:药物代谢酶、转运体;基因导向的精准用药
  • 邮箱:jiangf27@mail.sysu.edu.cn
  • 代表性论文:

1. Jiang F, Choi JY, Lee JH, Ryu S, Park ZW, Lee JG, Na HS, Lee SY, Oh WY, Chung MW, Choi SE. The influences of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of simvastatin, in relation to CYP3A4 inhibition. Pharmacogenomics. 2017 Apr;18(5):459-469. doi: 10.2217/pgs-2016-0199. Epub 2017 Mar 28.

 

2. Jiang F, Choi YJ, An HM, Lee H. A pharmacogenomic Study on the Pharmacokinetics of Tacrolimus in Healthy Volunteers Using the Affymetrix DMET Plus Platform. Pharmacogenomics J. 2016 Feb 16

3. Jiang F, Kim HD, Na HS, Lee SK, Ha JH, Seo DW, Choi JY, Hwang IY, Kim YH, Jeong HS, Kim JM, Chung MW. Effects of Drug Interactions and CYP2D6 Genotypes on Venlafaxine Pharmacokinetics: An Exploration of Biomarkers for Venlafaxine Pharmacodynamics. Psychopharmacology. 2015 Jun;232(11):1899-909

 

4. Abdelhady AM, Desta Z, Jiang F, Yeo CW, Shin JG, Overholser BR. Population pharmacogenetic-based pharmacokinetic modeling of efavirenz, 7-hydroxy- and 8-hydroxyefavirenz. J Clin Pharmacol. 2014 Jan;54(1):87-96

 

5. Jiang F, Desta Z, Shon JH, Yeo CW, Kim HS, Liu KH, Bae SK, Lee SS, Flockhart DA, Shin JG. Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl-metabolites: exploration of a novel CYP2B6 phenotyping index. Br J Clin Pharmacol. 2013 Jan;75(1):244-53

 

6. Jiang F, Yeo CW, Lee SS, Oh MK, Ghim JL, Shon JH, Kim EY, Shin JG. Effect of HNF4α Genetic polymorphism G60D on the pharmacokinetics of CYP2D6 substrate tolterodine in healthy Korean subjects. Pharmacogenet Genomics. 2013 Mar;23(3):175-9

 

7. Jiang F, Shin JG. Reply to: Letter to the editor “Impact of the CYP2C19*17 polymorphism on the pharmacokinetics and pharmacodynamics of proton pump inhibitors” J Clin Pharmacol. 2013 Mar;53(3):360

 

8. Lu Q, Jiang F, Xu R, Zhao XK, Zhong ZH, Zhang L, Jiang HY, Yi L, Hou Y, Zhu X. A pilot study on intravesical administration of curcumin for cystitis glandularis. Evid Based Complement Alternat Med. 2013;2013:269745

 

9. Kim KB, Kim HM, Jiang F, Yeo CW, Bae SK, Desta Z, Shin JG, Liu KH. Rapid and Simultaneous Determination of Efavirenz, 8-Hydroxyefavirenz, and 8,14-Dihydroxyefavirenz Using LC–MS–MS in Human Plasma and Application to Pharmacokinetics in Healthy Volunteers. Chromatographia. February 2011, Volume 73, Issue 3-4, pp 263-271

 

10. Fan L, Wang JC, Jiang F, Tan ZR, Chen Y, Li Q, Zhang W, Wang G, Lei HP, Hu DL, Wang D, Zhou HH. Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation. Eur J Clin Pharmacol. 2009 Apr;65(4):403-9